Hussein Kadhem Al-Hakeim Selected Research

Endorphins

12/2022	A pathway phenotype linking metabolic, immune, oxidative, and opioid pathways with comorbid depression, atherosclerosis, and unstable angina.
3/2021	Trace element, immune and opioid biomarkers of unstable angina, increased atherogenicity and insulin resistance: Results of machine learning.
1/2021	In schizophrenia, non-remitters and partial remitters to treatment with antipsychotics are qualitatively distinct classes with respect to neurocognitive deficits and neuro-immune biomarkers: results of soft independent modeling of class analogy.
4/2020	In major depression, increased kappa and mu opioid receptor levels are associated with immune activation.
11/2019	Development of a Novel Neuro-immune and Opioid-Associated Fingerprint with a Cross-Validated Ability to Identify and Authenticate Unknown Patients with Major Depression: Far Beyond Differentiation, Discrimination, and Classification.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Hussein Kadhem Al-Hakeim Research Topics

Disease

10	Insulin Resistance 01/2023 - 04/2015
10	Schizophrenia (Dementia Praecox) 11/2022 - 08/2015
9	Fatigue 11/2023 - 01/2020
8	Inflammation (Inflammations) 11/2023 - 08/2015
6	COVID-19 10/2023 - 01/2022
6	Post-Acute COVID-19 Syndrome 10/2023 - 01/2022
6	Psychotic Disorders (Schizoaffective Disorder) 10/2023 - 03/2020
6	Thalassemia 01/2023 - 07/2011
5	Iron Overload 01/2023 - 07/2011
5	Major Depressive Disorder (Major Depressive Disorders) 04/2020 - 01/2018
4	Infections 05/2023 - 05/2021
4	Type 2 Diabetes Mellitus (MODY) 11/2022 - 04/2015
4	Fibromyalgia (Fibrositis) 01/2022 - 01/2020
3	Chronic Fatigue Syndrome (Myalgic Encephalomyelitis) 01/2023 - 01/2021
2	Chronic Kidney Failure (Chronic Renal Failure) 11/2023 - 01/2023
2	Sleep Initiation and Maintenance Disorders (Insomnia) 04/2023 - 01/2023
2	Pre-Eclampsia (Preeclampsia) 01/2023 - 11/2020
2	Unstable Angina 12/2022 - 03/2021
2	Diabetes Complications 11/2022 - 12/2020
2	Treatment-Resistant Schizophrenia 01/2021 - 08/2020
2	beta-Thalassemia (Cooley's Anemia) 06/2020 - 11/2014
2	Rheumatoid Arthritis 01/2020 - 06/2019
1	Spontaneous Fractures (Pathological Fracture) 01/2023
1	Medically Unexplained Symptoms 01/2023
1	Bone Diseases (Bone Disease) 01/2023
1	Congenital Abnormalities (Deformity) 01/2023
1	Osteoporosis 01/2023
1	Metabolic Bone Diseases (Osteopenia) 01/2023
1	Atherosclerosis 12/2022
1	Hypertension (High Blood Pressure) 11/2022

Drug/Important Bio-Agent (IBA)

16	Biomarkers (Surrogate Marker)IBA 11/2023 - 01/2020
15	CalciumIBA 11/2023 - 07/2009
11	InterleukinsIBA 11/2023 - 01/2018
11	Proteins (Proteins, Gene)FDA Link 05/2023 - 11/2014
9	ZincIBA 11/2023 - 03/2021
9	MagnesiumIBA 12/2022 - 07/2009
8	Interleukin-10 (Interleukin 10)IBA 01/2023 - 01/2019
7	Opioid Analgesics (Opioids)IBA 12/2022 - 01/2019
6	AntioxidantsIBA 10/2023 - 03/2021
6	CopperIBA 01/2023 - 03/2021
6	Interleukin-6 (Interleukin 6)IBA 11/2022 - 08/2015
6	CytokinesIBA 12/2020 - 08/2015
5	C-Reactive ProteinIBA 01/2023 - 01/2022
5	EndorphinsIBA 12/2022 - 11/2019
5	HMGB1 Protein (HMG1)IBA 11/2022 - 01/2021
4	Peroxidase (Myeloperoxidase)IBA 05/2023 - 01/2022
4	AlbuminsIBA 01/2023 - 05/2021
4	mu Opioid Receptors (mu Opioid Receptor)IBA 12/2022 - 01/2019
4	IronIBA 05/2021 - 07/2011
4	Opioid Receptors (Opioid Receptor)IBA 01/2021 - 11/2019
3	Tryptophan (L-Tryptophan)FDA Link 10/2023 - 01/2023
3	Insulin (Novolin)FDA Link 05/2023 - 01/2018
3	A-factor (Streptomyces)IBA 01/2023 - 01/2022
3	Cholecalciferol (Vitamin D3)FDA Link 01/2023 - 03/2021
3	Glucose (Dextrose)FDA LinkGeneric 11/2022 - 01/2018
3	Trace Elements (Biometals)IBA 01/2022 - 06/2019
2	Methamphetamine (Desoxyn)FDA LinkGeneric 10/2023 - 11/2022
2	KynurenineIBA 10/2023 - 01/2023
2	N 30IBA 01/2023 - 11/2022
2	Interleukin-18 (Interleukin 18)IBA 01/2023 - 08/2015
2	Advanced Oxidation Protein Products (AOPP)IBA 01/2023 - 01/2022
2	Caspase 1 (ICE Protease)IBA 01/2023 - 01/2022
2	Hemoglobins (Hemoglobin)IBA 01/2023 - 05/2021
2	Malondialdehyde (Propanedial)IBA 01/2023 - 11/2014
2	oxidized low density lipoproteinIBA 11/2022 - 07/2009
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2022 - 08/2020
2	Interleukin-23 (Interleukin 23)IBA 11/2022 - 01/2022
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2022 - 01/2022
2	LipidsIBA 03/2021 - 07/2009
2	endomorphin 2IBA 01/2021 - 08/2020
2	Transferrin (beta 2 Transferrin)IBA 01/2021 - 11/2014
1	Calcium-Binding ProteinsIBA 11/2023
1	Myelin Basic ProteinIBA 11/2023
1	Glial Fibrillary Acidic ProteinIBA 11/2023
1	Intermediate Filament ProteinsIBA 11/2023
1	NestinIBA 11/2023
1	Leucine (L-Leucine)FDA Link 05/2023
1	Blood Glucose (Blood Sugar)IBA 05/2023
1	NucleotidesIBA 05/2023
1	InflammasomesIBA 05/2023
1	Glutathione PeroxidaseIBA 01/2023
1	AldehydesIBA 01/2023
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2023
1	CationsIBA 01/2023
1	CateninsIBA 01/2023
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2023
1	ChloridesIBA 01/2023
1	interleukin-21 (interleukin 21)IBA 11/2022
1	Interleukin-22 (IL-22)IBA 11/2022
1	Interleukin-17 (Interleukin 17)IBA 11/2022
1	AmidesIBA 03/2022
1	Advanced Glycation End ProductsIBA 01/2022
1	Angiotensin-Converting Enzyme 2IBA 01/2022
1	Receptor for Advanced Glycation End ProductsIBA 01/2022
1	CDw17 antigen (lactosylceramide)IBA 01/2022
1	IonsIBA 01/2022
1	Serotonin (5 Hydroxytryptamine)IBA 01/2022

Therapy/Procedure

4	Blood Transfusion (Blood Transfusions) 01/2023 - 06/2020
2	Therapeutics 01/2021 - 08/2015
1	Renal Dialysis (Hemodialysis) 01/2023